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Prevention of diabetes mellitus in the BB/W rat with Cyclosporin-A.

Autoimmune diabetes mellitus occurs spontaneously in 40-60% of a colony of BioBreeding/Worcester rats. Pretreatment of susceptible animals for 10-day intervals prior to 70 days of age with Cyclosporin-A (CSA) significantly reduced the frequency and delayed the onset of diabetes. The relatively narro...

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Bibliografiske detaljer
Main Authors: Like, A. A., Dirodi, V., Thomas, S., Guberski, D. L., Rossini, A. A.
Format: Artigo
Sprog:Inglês
Udgivet: 1984
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900571/
https://ncbi.nlm.nih.gov/pubmed/6385729
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