Herpes simplex virus type 1 alkaline nuclease is required for efficient processing of viral DNA replication intermediates.

Mutations in the alkaline nuclease gene of herpes simplex type 1 (HSV-1) (nuc mutations) induce almost wild-type levels of viral DNA; however, mutant viral yields are 0.1 to 1% of wild-type yields (L. Shao, L. Rapp, and S. Weller, Virology 195:146-162, 1993; R. Martinez, L. Shao, J.C. Bronstein, P.C...

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Pubblicato in:	J Virol
Autori principali:	Martinez, R, Sarisky, R T, Weber, P C, Weller, S K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190043/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8642627/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.4.2075-2085.1996
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