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Mutations in the zinc-binding motif of the reovirus capsid protein delta 3 eliminate its ability to associate with capsid protein mu 1.

Reovirus capsid protein delta 3 binds both double-stranded RNA (dsRNA) and zinc. Previous studies have revealed that the amino-terminal zinc finger is not required for the ability of delta 3 to bind dsRNA. We expressed wild-type and mutant delta 3 molecules by in vitro transcription/translation to e...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Shepard, D A, Ehnstrom, J G, Skinner, P J, Schiff, L A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190041/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.2065-2068.1996
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