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Infectivity Determinants of the Hepatitis B Virus Pre-S Domain Are Confined to the N-Terminal 75 Amino Acid Residues

The N-terminal pre-S domain of the large hepatitis B virus (HBV) envelope protein plays a pivotal role at the initial step of the viral entry pathway. In the present study, the entire pre-S domain was mapped for infectivity determinants, following a reverse-genetics approach and using in vitro infec...

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Autors principals: Blanchet, Matthieu, Sureau, Camille
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900317/
https://ncbi.nlm.nih.gov/pubmed/17376925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00096-07
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