Purification of Host Cell Enzymes Involved in Adeno-Associated Virus DNA Replication

Adeno-associated virus (AAV) replicates its DNA by a modified rolling-circle mechanism that exclusively uses leading strand displacement synthesis. To identify the enzymes directly involved in AAV DNA replication, we fractionated adenovirus-infected crude extracts and tested them in an in vitro repl...

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Bibliografiske detaljer
Main Authors: Nash, Kevin, Chen, Weijun, McDonald, William F., Zhou, Xiaohuai, Muzyczka, Nicholas
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900299/
https://ncbi.nlm.nih.gov/pubmed/17360744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02651-06
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