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Human Immunodeficiency Virus Bearing a Disrupted Central DNA Flap Is Pathogenic In Vivo

The central DNA flap is an important component of lentiviral vectors, but its significance in the context of wild-type human immunodeficiency virus (HIV) is currently unclear. To address this issue, we have compared the in vitro infection kinetics of NL4-3 with those of a flap-deficient mutant and e...

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Hlavní autoři: Marsden, Matthew D., Zack, Jerome A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900283/
https://ncbi.nlm.nih.gov/pubmed/17392373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00203-07
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