Cytomegalovirus Infection in Gambian Infants Leads to Profound CD8 T-Cell Differentiation

Cytomegalovirus (CMV) infection is endemic in Gambian infants, with 62% infected by 3 months and 85% by 12 months of age. We studied the CD8 T-cell responses of infants to CMV following primary infection. CMV-specific CD8 T cells, identified with tetramers, showed a fully differentiated phenotype (C...

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Autors principals: Miles, David J. C., van der Sande, Marianne, Jeffries, David, Kaye, Steve, Ismaili, Jamila, Ojuola, Olubukola, Sanneh, Mariama, Touray, Ebrima S., Waight, Pauline, Rowland-Jones, Sarah, Whittle, Hilton, Marchant, Arnaud
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900274/
https://ncbi.nlm.nih.gov/pubmed/17376923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00052-07
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