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Tyrosine 3 of Poliovirus Terminal Peptide VPg(3B) Has an Essential Function in RNA Replication in the Context of Its Precursor Protein, 3AB

Poliovirus (PV) VPg is a genome-linked protein that is essential for the initiation of viral RNA replication. It has been well established that RNA replication is initiated when a molecule of UMP is covalently linked to the hydroxyl group of a tyrosine (Y3) in VPg by the viral RNA polymerase 3D(pol)...

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Detalhes bibliográficos
Main Authors: Liu, Ying, Franco, David, Paul, Aniko V., Wimmer, Eckard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900252/
https://ncbi.nlm.nih.gov/pubmed/17360746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02350-06
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