Enhanced Replication of Human T-Cell Leukemia Virus Type 1 in T Cells from Transgenic Rats Expressing Human CRM1 That Is Regulated in a Natural Manner

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia (ATL). To develop a better animal model for the investigation of HTLV-1 infection, we established a transgenic (Tg) rat carrying the human CRM1 (hCRM1) gene, which encodes a viral RNA transporter that is a sp...

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Detalhes bibliográficos
Main Authors: Takayanagi, Ryo, Ohashi, Takashi, Yamashita, Eizaburo, Kurosaki, Yohei, Tanaka, Kumiko, Hakata, Yoshiyuki, Komoda, Yasumasa, Ikeda, Satoru, Tsunetsugu-Yokota, Yasuko, Tanaka, Yuetsu, Shida, Hisatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900248/
https://ncbi.nlm.nih.gov/pubmed/17360758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02811-06
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