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Immunoadhesins Containing Pre-S Domains of Hepatitis B Virus Large Envelope Protein Are Secreted and Inhibit Virus Infection

Hepatitis B virus (HBV) replication produces three envelope proteins (L, M, and S) that have a common C terminus. L, the largest, contains a domain, pre-S1, not present on M. Similarly M contains a domain, pre-S2, not present on S. The pre-S1 region has important functions in the HBV life cycle. Thu...

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Detalhes bibliográficos
Main Authors: Chai, Ning, Gudima, Severin, Chang, Jinhong, Taylor, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900235/
https://ncbi.nlm.nih.gov/pubmed/17329331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02865-06
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