Mitogen-Activated Protein Kinases Activate the Nuclear Localization Sequence of Human Papillomavirus Type 11 E1 DNA Helicase To Promote Efficient Nuclear Import

Human and animal papillomavirus DNA replicates as multicopy nuclear plasmids. Replication requires two viral proteins, the origin-recognition protein E2 and the replicative DNA helicase E1. Using genetic, biochemical, and immunofluorescence assays, we demonstrated that efficient nuclear import of th...

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Detalles Bibliográficos
Main Authors: Yu, Jei-Hwa, Lin, Biing Yuan, Deng, Wentao, Broker, Thomas R., Chow, Louise T.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2007
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900230/
https://ncbi.nlm.nih.gov/pubmed/17344281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02480-06
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