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Rab 5 Is Required for the Cellular Entry of Dengue and West Nile Viruses
The mechanisms of cellular entry of dengue and West Nile viruses are not well characterized. We show that both these viruses enter HeLa cells by clathrin-dependent endocytosis and require vacuolar acidic pH. Inhibition of the GTPase Rab 5 or 7, which regulates transport to early or late endosomes, r...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1900185/ https://ncbi.nlm.nih.gov/pubmed/17301152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02210-06 |
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