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Primary CD4(+) T-Cell Responses Provide both Helper and Cytotoxic Functions during Epstein-Barr Virus Infection and Transformation of Fetal Cord Blood B Cells

Most humans carry Epstein-Barr virus (EBV) in circulating memory B cells as a latent infection that is controlled by an immune response. When infected by EBV, B lymphocytes in fetal cord blood are readily transformed to lymphoblastoid cell lines (LCL). It is frequently assumed that this high efficie...

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Detalhes bibliográficos
Main Authors: MacArthur, Georgina J., Wilson, A. Douglas, Birchall, Martin A., Morgan, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900140/
https://ncbi.nlm.nih.gov/pubmed/17314172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02608-06
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