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Identification of a Novel C-Terminal Cleavage of Crimean-Congo Hemorrhagic Fever Virus PreG(N) That Leads to Generation of an NS(M) Protein

The structural glycoproteins of Crimean-Congo hemorrhagic fever virus (CCHFV; genus Nairovirus, family Bunyaviridae) are derived through endoproteolytic cleavage of a 1,684-amino-acid M RNA segment-encoded polyprotein. This polyprotein is cotranslationally cleaved into the PreG(N) and PreG(C) precur...

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Detalhes bibliográficos
Main Authors: Altamura, Louis A., Bertolotti-Ciarlet, Andrea, Teigler, Jeffrey, Paragas, Jason, Schmaljohn, Connie S., Doms, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900101/
https://ncbi.nlm.nih.gov/pubmed/17409136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02730-06
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