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Mutagenesis of the Herpesvirus Saimiri Terminal Repeat Region Reveals Important Elements for Virus Production

Deletion of the terminal repeats (TR) from herpesvirus saimiri (HVS) renders it unable to produce infectious virus or generate plaques. However, a TR-deleted HVS bacterial artificial chromosome can form replication compartments. Complementation of this mutant shows that one copy of the TR, plus the...

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Autors principals: White, Robert E., Carline, Lindsay, Allday, Martin J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900079/
https://ncbi.nlm.nih.gov/pubmed/17428860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02579-06
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