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A novel murine retrovirus identified during testing for helper virus in human gene transfer trials.

An important requirement for the use of retroviral vectors in human gene transfer experiments is the avoidance of human exposure to replication-competent (helper) retroviruses. To meet this requirement, we used a sensitive marker rescue assay for helper virus to screen vector-transduced cells prior...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Miller, A D, Bonham, L, Alfano, J, Kiem, H P, Reynolds, T, Wolgamot, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190007/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627704/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1804-1809.1996
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