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Identification of a herpesvirus Saimiri cis-acting DNA fragment that permits stable replication of episomes in transformed T cells.

Herpesvirus saimiri is a lymphotropic herpesvirus capable of immortalizing and transforming T cells both in vitro and in vivo. Immortalized and transformed T cells harbor several copies of the viral genome as a persisting genome. The mapping of the cis-acting genetic cis-acting segment (oriP) requir...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Kung, S H, Medveczky, P G
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189998/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627695/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1738-1744.1996
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