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Rbm15 Modulates Notch-Induced Transcriptional Activation and Affects Myeloid Differentiation

RBM15 is the fusion partner with MKL in the t(1;22) translocation of acute megakaryoblastic leukemia. To understand the role of the RBM15-MKL1 fusion protein in leukemia, we must understand the normal functions of RBM15 and MKL. Here, we show a role for Rbm15 in myelopoiesis. Rbm15 is expressed at h...

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Bibliographic Details
Main Authors: Ma, Xianyong, Renda, Matthew J., Wang, Lin, Cheng, Ee-chun, Niu, Chao, Morris, Stephan W., Chi, Andrew S., Krause, Diane S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899951/
https://ncbi.nlm.nih.gov/pubmed/17283045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01339-06
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