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Role for Furin in Tumor Necrosis Factor Alpha-Induced Activation of the Matrix Metalloproteinase/Sphingolipid Mitogenic Pathway
Neutral sphingomyelinase (nSMase), the initial enzyme of the sphingolipid signaling pathway, is thought to play a key role in cellular responses to tumor necrosis factor alpha (TNF-α), such as inflammation, proliferation, and apoptosis. The mechanism of TNF-α-induced nSMase activation is only partly...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Microbiology
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1899924/ https://ncbi.nlm.nih.gov/pubmed/17283058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01485-06 |
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