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NHERF1/EBP50 Head-to-Tail Intramolecular Interaction Masks Association with PDZ Domain Ligands

Loss of cell polarity is one of the initial alterations in the development of human epithelial cancers. Na(+)/H(+) exchanger regulatory factor (NHERF) homologous adaptors 1 and 2 are membrane-associated proteins composed of two amino (N)-terminal PDZ domains and an ezrin-radixin-moesin (ERM)-binding...

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Autori principali: Morales, Fabiana C., Takahashi, Yoko, Momin, Safan, Adams, Henry, Chen, Xiaomin, Georgescu, Maria-Magdalena
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899890/
https://ncbi.nlm.nih.gov/pubmed/17242191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01372-06
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