Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions.

The E2 gene products of papillomavirus play key roles in viral replication, both as regulators of viral transcription and as auxiliary factors that act with E1 in viral DNA replication. We have carried out a detailed structure-function analysis of conserved amino acids within the N-terminal domain o...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Sakai, H, Yasugi, T, Benson, J D, Dowhanick, J J, Howley, P M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627680/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1602-1611.1996
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