Acute inflammation and a Shwartzman-like reaction induced by interleukin-1 and tumor necrosis factor. Synergistic action of the cytokines in the induction of inflammation and microvascular injury.

A Shwartzman-like reaction was elicited in rabbits by preparing the skin with intradermal injections of recombinant human tumor necrosis factor alpha (TNF alpha) and recombinant human interleukin-1 (IL-1 alpha or beta). The animals were challenged intravenously with endotoxin or by intravascular act...

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Detalles Bibliográficos
Main Authors: Movat, H. Z., Burrowes, C. E., Cybulsky, M. I., Dinarello, C. A.
Formato: Artigo
Idioma:Inglês
Publicado: 1987
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899823/
https://ncbi.nlm.nih.gov/pubmed/3501244
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