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Monoclonal antibodies against human immunodeficiency virus type 1 integrase: epitope mapping and differential effects on integrase activities in vitro.

Human immunodeficiency virus type 1 (HIV-1) integrase (IN) catalyzes the integration of viral DNA into the host chromosome, an essential step in retroviral replication. As a tool to study the structure and function of this enzyme, monoclonal antibodies (MAbs) against HIV-1 IN were produced. Epitope...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Nilsen, B M, Haugan, I R, Berg, K, Olsen, L, Brown, P O, Helland, D E
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189980/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8627677/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.3.1580-1587.1996
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