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Parthenolide Inhibits IκB Kinase, NF-κB Activation, and Inflammatory Response in Cystic Fibrosis Cells and Mice

Cystic fibrosis (CF) is characterized by prolonged and excessive inflammatory responses in the lung and increased activation of NF-κB. Parthenolide is a sesquiterpene lactone derived from the plant feverfew, which has been used in folk medicine for anti-inflammatory activity. Several studies suggest...

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Main Authors: Saadane, Aicha, Masters, Sophia, DiDonato, Joseph, Li, Jingfeng, Berger, Melvin
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899341/
https://ncbi.nlm.nih.gov/pubmed/17272824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0323OC
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