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ALK-5 Mediates Endogenous and TGF-β1–Induced Expression of Connective Tissue Growth Factor in Embryonic Lung
Transforming growth factor-β1 (TGF-β1) has been implicated as a major negative regulator of lung branching morphogenesis. Since connective tissue growth factor (CTGF) is a downstream mediator of TGF-β1 effects on mesenchymal cells, we hypothesized that TGF-β1 induces CTGF expression in mouse embryon...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Thoracic Society
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1899336/ https://ncbi.nlm.nih.gov/pubmed/17197570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0320OC |
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