Asymmetric Dimethylarginine Induces Oxidative and Nitrosative Stress in Murine Lung Epithelial Cells

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) produced by epithelial and inflammatory cells are key mediators of the chronic airway inflammation of asthma. Low L-arginine levels can result in the uncoupling of nitric oxide synthase (NOS) leading to production of both ROS and RNS....

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Detalhes bibliográficos
Main Authors: Wells, Sandra M., Holian, Andrij
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2007
Assuntos:
Oxidative-Nitrosative Stress and Post-Translational Protein Modifications: Implications to Lung Structure-Function Relations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899333/
https://ncbi.nlm.nih.gov/pubmed/17158357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0302SM
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