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Silica-Directed Mast Cell Activation Is Enhanced by Scavenger Receptors

Inhalation of crystalline silica results in pulmonary fibrosis and silicosis. It has been suggested that mast cells play a role in these conditions. How mast cells would influence pathology is unknown. We thus explored mast cell interactions with silica in vitro and in B6.Cg-kit(W-sh) mast cell–defi...

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Bibliographic Details
Main Authors: Brown, Jared M., Swindle, Emily J., Kushnir-Sukhov, Nataliya M., Holian, Andrij, Metcalfe, Dean D.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899302/
https://ncbi.nlm.nih.gov/pubmed/16902192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0197OC
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