Impact of Low and High Tidal Volumes on the Rat Alveolar Epithelial Type II Cell Proteome

Rationale: Mechanical ventilation with high tidal volumes leads to increased permeability, generation of inflammatory mediators, and damage to alveolar epithelial cells (ATII). Objectives: To identify changes in the ATII proteome after two different ventilation strategies in rats. Methods: Rats (n =...

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Main Authors: Hirsch, Jan, Hansen, Kirk C., Sapru, Anil, Frank, James A., Chalkley, Robert J., Fang, Xiaohui, Trinidad, Jonathan C., Baker, Peter, Burlingame, Alma L., Matthay, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2007
Assuntos:
C. Critical Care
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899270/
https://ncbi.nlm.nih.gov/pubmed/17363773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200605-621OC
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