Heritability of Lung Disease Severity in Cystic Fibrosis

Rationale: Obstructive lung disease, the major cause of mortality in cystic fibrosis (CF), is poorly correlated with mutations in the disease-causing gene, indicating that other factors determine severity of lung disease. Objectives: To quantify the contribution of modifier genes to variation in CF...

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Hlavní autoři: Vanscoy, Lori L., Blackman, Scott M., Collaco, Joseph M., Bowers, Amanda, Lai, Teresa, Naughton, Kathleen, Algire, Marilyn, McWilliams, Rita, Beck, Suzanne, Hoover-Fong, Julie, Hamosh, Ada, Cutler, Dave, Cutting, Garry R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2007
Témata:
D. Cystic Fibrosis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899267/
https://ncbi.nlm.nih.gov/pubmed/17332481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200608-1164OC
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