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Transcription Factor NF-κB Is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complex in Hippocampal Neurons

BACKGROUND: Long-term changes in synaptic plasticity require gene transcription, indicating that signals generated at the synapse must be transported to the nucleus. Synaptic activation of hippocampal neurons is known to trigger retrograde transport of transcription factor NF-κB. Transcription facto...

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Bibliografische gegevens
Hoofdauteurs: Mikenberg, Ilja, Widera, Darius, Kaus, Aljoscha, Kaltschmidt, Barbara, Kaltschmidt, Christian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899224/
https://ncbi.nlm.nih.gov/pubmed/17622342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000589
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