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Transcription Factor NF-κB Is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complex in Hippocampal Neurons

BACKGROUND: Long-term changes in synaptic plasticity require gene transcription, indicating that signals generated at the synapse must be transported to the nucleus. Synaptic activation of hippocampal neurons is known to trigger retrograde transport of transcription factor NF-κB. Transcription facto...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mikenberg, Ilja, Widera, Darius, Kaus, Aljoscha, Kaltschmidt, Barbara, Kaltschmidt, Christian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899224/
https://ncbi.nlm.nih.gov/pubmed/17622342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000589
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