Transcription Factor NF-κB Is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complex in Hippocampal Neurons

BACKGROUND: Long-term changes in synaptic plasticity require gene transcription, indicating that signals generated at the synapse must be transported to the nucleus. Synaptic activation of hippocampal neurons is known to trigger retrograde transport of transcription factor NF-κB. Transcription facto...

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Bibliographic Details
Main Authors: Mikenberg, Ilja, Widera, Darius, Kaus, Aljoscha, Kaltschmidt, Barbara, Kaltschmidt, Christian
Format: Artigo
Language:Inglês
Published: Public Library of Science 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899224/
https://ncbi.nlm.nih.gov/pubmed/17622342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000589
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