Transcription Factor NF-κB Is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complex in Hippocampal Neurons

BACKGROUND: Long-term changes in synaptic plasticity require gene transcription, indicating that signals generated at the synapse must be transported to the nucleus. Synaptic activation of hippocampal neurons is known to trigger retrograde transport of transcription factor NF-κB. Transcription facto...

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Hauptverfasser: Mikenberg, Ilja, Widera, Darius, Kaus, Aljoscha, Kaltschmidt, Barbara, Kaltschmidt, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899224/
https://ncbi.nlm.nih.gov/pubmed/17622342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000589
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