Stored Packed Red Blood Cell Transfusion Up-regulates Inflammatory Gene Expression in Circulating Leukocytes

SUMMARY BACKGROUND DATA: The transfusion of more than 6 units of packed red blood cells (PRBCs) within the first 12 hours of injury is the strongest independent predictor of multiple organ failure (MOF). This suggests that stored blood contains bioactive factors that may modify the immunoinflammator...

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Detalhes bibliográficos
Main Authors: Escobar, Guillermo A., Cheng, Aaron M., Moore, Ernest E., Johnson, Jeffrey L., Tannahill, Cynthia, Baker, Henry V., Moldawer, Lyle L., Banerjee, Anirban
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899205/
https://ncbi.nlm.nih.gov/pubmed/17592301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000264507.79859.f9
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