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In vivo assay of p53 function in homologous recombination between simian virus 40 chromosomes.

To investigate a possible role of p53 in DNA exchange mechanisms, we have developed a model system which allows us to quantify homologous recombination rates in eukaryotic cells. We generated two types of simian virus 40 (SV40) whose genomes were mutated in such a way that upon double infection of m...

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Main Authors: Wiesmüller, L, Cammenga, J, Deppert, W W
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC189874/
https://ncbi.nlm.nih.gov/pubmed/8551610
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