Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes.

Apoptosis has been proposed to mediate CD4+ T-cell depletion in human immunodeficiency virus (HIV)-infected individuals. Interaction of Fas ligand (FasL) with Fas (CD95) results in lymphocyte apoptosis, and increased susceptibility to Fas-mediated apoptosis has been demonstrated in lymphocytes from...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Badley, A D, McElhinny, J A, Leibson, P J, Lynch, D H, Alderson, M R, Paya, C V
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189805/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8523526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.1.199-206.1996
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