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Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease.

In addition to NS3 protease, the NS4A protein is required for efficient cleavage of the nonstructural protein region of the hepatitis C virus polyprotein. To investigate the function and the sequence of NS4A required for the enhancement of NS3 protease activity, we developed an in vitro NS3 protease...

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Detalhes bibliográficos
Main Authors: Shimizu, Y, Yamaji, K, Masuho, Y, Yokota, T, Inoue, H, Sudo, K, Satoh, S, Shimotohno, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189796/
https://ncbi.nlm.nih.gov/pubmed/8523516
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