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Complete inhibition of virion assembly in vivo with mutant procapsid RNA essential for phage phi 29 DNA packaging.

A highly efficient method for the inhibition of bacteriophage phi 29 assembly was developed with the use of mutant forms of the viral procapsid (or packaging) RNA (pRNA) indispensable for phi 29 DNA packaging. Phage phi 29 assembly was severely reduced in vitro in the presence of mutant pRNA and com...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Trottier, M, Zhang, C, Guo, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8523569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.1.55-61.1996
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