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Epstein-Barr virus induction of recombinase-activating genes RAG1 and RAG2.

In experimental B-cell infections, Epstein-Barr virus induced sustained expression of V(D)J recombinase-activating genes RAG1 and RAG2, whose aberrant activity has been implicated in chromosomal translocations in B-cell neoplasms. In cell lines in which RAG1 and RAG2 were detected, virus integrated...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Srinivas, S K, Sixbey, J W
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189773/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7494341/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.12.8155-8158.1995
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