Genetic and structural analysis of a virulence determinant in polyomavirus VP1.

The LID strain of polyomavirus differs from other laboratory strains in causing a rapidly lethal infection of newborn C3H/Bi mice. This virulent behavior of LID was attenuated by dilution, yet at sublethal doses LID was able to induce tumors at a high frequency, like its parent virus PTA. By constru...

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Autors principals: Bauer, P H, Bronson, R T, Fung, S C, Freund, R, Stehle, T, Harrison, S C, Benjamin, T L
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC189737/
https://ncbi.nlm.nih.gov/pubmed/7494305
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