Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation.

Processing of the hepatitis C virus polyprotein is mediated by host cell signalases and at least two virally encoded proteinases. Of these, the serine-type proteinase encompassing the amino-terminal one-third of NS3 is responsible for cleavage at the four sites carboxy terminal of NS3. The activity...

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Pubblicato in:	J Virol
Autori principali:	Bartenschlager, R, Lohmann, V, Wilkinson, T, Koch, J O
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189690/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7494258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.12.7519-7528.1995
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