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Point mutations in the herpes simplex virus type 1 Vmw110 RING finger helix affect activation of gene expression, viral growth, and interaction with PML-containing nuclear structures.

Herpes simplex virus type 1 immediate-early protein Vmw110 (also known as ICP0) has been implicated in the control of the balance between the lytic and latent states, but the precise mechanisms by which it exerts its effects are unknown. Vmw110 includes a characteristic zinc binding domain, termed t...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Everett, R, O'Hare, P, O'Rourke, D, Barlow, P, Orr, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189666/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7474166/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.11.7339-7344.1995
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