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Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp

The Paks (p21-activated kinases) Pak1, Pak2 and Pak3 are among the most studied effectors of the Rho-family GTPases, Rac, Cdc42 (cell division cycle 42) and Chp (Cdc42 homologous protein). Pak kinases influence a variety of cellular functions, but the process of Pak down-regulation, following activa...

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Detalhes bibliográficos
Main Authors: Weisz Hubsman, Monika, Volinsky, Natalia, Manser, Edward, Yablonski, Deborah, Aronheim, Ami
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896286/
https://ncbi.nlm.nih.gov/pubmed/17355222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061696
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