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A Comprehensive Calorimetric Investigation of an Entropically Driven T Cell Receptor-Peptide/Major Histocompatibility Complex Interaction

The αβ T cell receptor (TCR) is responsible for recognizing peptides bound and “presented” by major histocompatibility complex (MHC) molecules. We recently reported that at 25°C the A6 TCR, which recognizes the Tax peptide presented by the class I MHC human leukocyte antigen-A*0201 (HLA-A2), binds w...

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Bibliografske podrobnosti
Main Authors: Armstrong, Kathryn M., Baker, Brian M.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896243/
https://ncbi.nlm.nih.gov/pubmed/17449678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.104570
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