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Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation.

The Vpr gene product of human immunodeficiency virus type 1 is a virion-associated protein that is important for efficient viral replication in nondividing cells such as macrophages. At the cellular level, Vpr is primarily localized in the nucleus when expressed in the absence of other viral protein...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Yao, X J, Subbramanian, R A, Rougeau, N, Boisvert, F, Bergeron, D, Cohen, E A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189623/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7474123/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.11.7032-7044.1995
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