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CD13/APN regulates endothelial invasion and filopodia formation

CD13/aminopeptidase N is a transmembrane peptidase that is induced in the vasculature of solid tumors and is a potent angiogenic regulator. Here, we demonstrate that CD13 controls endothelial cell invasion in response to the serum peptide bradykinin by facilitating signal transduction at the level o...

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Detalhes bibliográficos
Main Authors: Petrovic, Nenad, Schacke, Wolfgang, Gahagan, J. Reed, O'Conor, Catherine A., Winnicka, Beata, Conway, Rebecca E., Mina-Osorio, Paola, Shapiro, Linda H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1896108/
https://ncbi.nlm.nih.gov/pubmed/17363739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-002931
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