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Integrated network analysis identifies nitric oxide response networks and dihydroxyacid dehydratase as a crucial target in Escherichia coli

Nitric oxide (NO) is used by mammalian immune systems to counter microbial invasions and is produced by bacteria during denitrification. As a defense, microorganisms possess a complex network to cope with NO. Here we report a combined transcriptomic, chemical, and phenotypic approach to identify dir...

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Autores principales: Hyduke, Daniel R., Jarboe, Laura R., Tran, Linh M., Chou, Katherine J. Y., Liao, James C.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895976/
https://ncbi.nlm.nih.gov/pubmed/17494765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610888104
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