Extreme fitness differences in mammalian and insect hosts after continuous replication of vesicular stomatitis virus in sandfly cells.

Continuous, persistent replication of a wild-type strain of vesicular stomatitis virus in cultured sandfly cells for 10 months profoundly decreased virus replicative fitness in mammalian cells and greatly increased fitness in sandfly cells. After persistent infection of sandfly cells, fitness was ov...

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Bibliografiske detaljer
Main Authors: Novella, I S, Clarke, D K, Quer, J, Duarte, E A, Lee, C H, Weaver, S C, Elena, S F, Moya, A, Domingo, E, Holland, J J
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189592/
https://ncbi.nlm.nih.gov/pubmed/7474092
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