The role of KAHRP domains in knob formation and cytoadherence of P falciparum-infected human erythrocytes

Surface protrusions of Plasmodium falciparum-infected erythrocytes, called knobs, display focal aggregates of P falciparum erythrocyte membrane protein 1 (PfEMP1), the adhesion ligand binding endothelial-cell receptors. The resulting sequestration of infected erythrocytes in tissues represents an im...

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Main Authors: Rug, Melanie, Prescott, Stuart W., Fernandez, Kate M., Cooke, Brian M., Cowman, Alan F.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Hematology 2006
Teme:
Red Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895844/
https://ncbi.nlm.nih.gov/pubmed/16507777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-11-4624
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