Clinical implication of centrosome amplification in plasma cell neoplasm

The mechanisms underlying aneuploidy in multiple myeloma (MM) are unclear. Centrosome amplification has been implicated as the cause of chromosomal instability in a variety of tumors and is a potential mechanism causing aneuploidy in MM. Using immunofluorescent (IF) staining, centrosome amplificatio...

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Detalhes bibliográficos
Main Authors: Chng, Wee J., Ahmann, Greg J., Henderson, Kim, Santana-Davila, Rafael, Greipp, Philip R., Gertz, Morie A., Lacy, Martha Q., Dispenzieri, Angela, Kumar, Shaji, Rajkumar, S. Vincent, Lust, John A., Kyle, Robert A., Zeldenrust, Steven R., Hayman, Suzanne R., Fonseca, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895774/
https://ncbi.nlm.nih.gov/pubmed/16373658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3810
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